CNRS Research Director, Université Paris-Saclay
Université Paris-Saclay, CNRS, Laboratoire de Physique des Solides, 91405 Orsay, France
Guillaume Tresset obtained a PhD in plasma physics at the French Atomic Energy Agency (CEA) in 2002. He worked as a postdoctoral fellow at the University of Tokyo in Japan from 2002 to 2004 on microfluidic devices for the manipulation of lipid vesicles and molecular motors, then at the Institute of Bioengineering and Nanotechnology in Singapore from 2005 to 2008 on artificial viruses. He joined the French National Center for Scientific Research (CNRS) in 2008 and he is currently Research Director at the Laboratoire de Physique des Solides (Université Paris-Saclay, France) where he heads the team Self-Organized Biological Systems since 2019. He has published 54 research articles (h-index: 22) and he has given 11 invited talks in international conferences. He was elected as a member of the National Committee for Scientific Research (CoNRS) from 2016 to 2019, and he has reviewed numerous grant applications for national and international agencies.
Areas of expertise
Biophysics and bio-inspired systems, viruses, DNA complexes, microfluidics and X-ray/neutron scattering.
- S. Panahandeh, S. Li, L. Marichal, R. Leite Rubim, G. Tresset, R. Zandi (2020). “How a virus circumvents energy barriers to form symmetric shells”. ACS Nano to be published.
- J.-P. Gomez, G. Tresset, C. Pichon, P. Midoux (2019). “Improved histidinylated lPEI polyplexes for skeletal muscle cells transfection”. Int. J. Pharm. 559 58-67.
- M. Chevreuil, D. Law-Hine, J. Chen, S. Bressanelli, S. Combet, D. Constantin, J. Degrouard, J. Möller, M. Zeghal, G. Tresset (2018). “Nonequilibrium self-assembly dynamics of icosahedral viral capsids packaging genome or polyelectrolyte”. Nat. Commun. 9 3071.
- M. Ni, G. Tresset, C. Iliescu (2017). “Self-Assembled polysulfone nanoparticles using microfluidic chip”. Sens. Actuators B 252 458-462.
- C. Iliescu, G. Tresset (2015). “Microfluidics-driven Strategy for size-controlled DNA compaction by slow diffusion through water stream”. Chem. Mater. 27 8193-8197.
- G. Tresset, M. Tatou, C. Le Cœur, M. Zeghal, V. Bailleux, A. Lecchi, K. Brach, M. Klekotko, L. Porcar (2014). “Weighing polyelectrolytes packaged in viruslike particles”. Phys. Rev. Lett. 113 128305.
- B. Maury, C. Gonçalves, G. Tresset, M. Zeghal, H. Cheradame, P. Guégan, C. Pichon, P. Midoux (2014). “Influence of pDNA availability on transfection efficiency of polyplexes in non-proliferative cells”. Biomaterials 35 5977-5985.
Main current grants
- “Virus-inspired nanoparticles”. ANR 2017-2021.
- “Marangoni-based rapid chemical characterization”. ANR 2017-2021.
- “Solving Levinthal’s paradox for genome packaging in icosahedral ssRNA viruses”. ANR 2016-2020.